Dental stem cells（DSCs） belongs to adult stem cells (ASCs), which originate from the early development of the mesoderm with high self-renewal and multi-directional differentiation potential. Dental mesenchymal stem cells are mesenchymal stem cells extracted from dental tissue，they can be used as seed cells for periodontal tissue regeneration due to their good regeneration and differentiation potential and low immunogenicity. To date, different dental mesenchymal stem cells have been isolated and characterized based on their sources: Dental Pulp Stem Cells (DPSCs); Periodontal Ligament Stem Cells (PDLSCs); Gingival Mesenchymal Stem Cells (GMSCs); Stem cells from Human Exfoliated Deciduous teeth (SHED); Dental Follicle Progenitor Cells (DFPCs); and Stem Cells from Apical Papilla (SCAP).
1. High security
Dental stem cells have low immunogenicity and does not require typing, which can be used by the whole family for three generations.
2. Convenient collection
Dental stem cells are collected from deciduous teeth, teeth that need to be extracted during orthodontic treatment, and third molars that need to be extracted. Collection is convenient and it is a reuse of the above teeth.
3. Wider application range
Dental stem cells can be applied to disease intervention, treatment, beauty, anti-aging, organ regeneration, etc
4. High biological activity
Dental stem cells proliferation is fast, and its biological activity is more than three times that of stem cells from other sources.
5. Strong immune regulation ability
Dental stem cells can enhance immunity, prevent diseases, and fight against aging.
6. More usage times
Dental stem cells can be expanded and cultured in vitro, and one tooth can be used multiple times by multiple people.
一、 Customer consultation and registration information
Confirm if the teeth can be extracted and stored. If deciduous teeth can function without shaking, they are not suitable for extraction. When teeth begin to loosen, it is best to collect when one-third of the root tips are absorbed. If all the roots are absorbed, leaving only the crown. At this time, stem cells cannot be extracted, and the judgment criteria are determined by the dentist.
二、 Blood collection, testing and evaluation
三、 Tooth collection, cold chain transportation
四、 Sample reception, registration and verification
五、 Cell preparation, detection and evaluation
六、 Cell cryopreservation, report distribution
七、 Regular monitoring to ensure safety
At present, medical research shows that stem cells have shown good therapeutic effects in the treatment of various diseases:
Childhood: cerebral palsy, brittle bone disease, progressive muscular dystrophy, autism
Adulthood: cirrhosis, systemic lupus erythematosus, Rheumatoid arthritis, tumor, corneal injury, tendon injury, anti-aging, Periodontal disease, spinal cord injury, beauty, scald
Senile period: myocardial infarction, stroke, senile dementia, Parkinson's disease, diabetes, femoral head necrosis, osteoporosis, biological root regeneration
Who can store dental stem cells?
Individuals who are physically healthy, have no family history of genetic diseases, and have normal routine testing can sign relevant documents and complete relevant procedures. After passing the testing, dental stem cells can be preserved.
What are the standards for collecting deciduous teeth?
Freshly extracted deciduous teeth are judged by dentists to determine the condition of the tooth body and pulp, and select deciduous teeth without symptoms such as caries, pulp inflammation, and pulp necrosis; Select at least 1/3 of the remaining primary incisors or primary canines, and it is not recommended to use primary molars as samples; Healthy deciduous molars that require early extraction due to orthodontic treatment can also be included in the collection criteria.
Can childrens dental caries be stored?
Caries affect the activity of stem cells. Experts suggest that considering the lifestyle habits of modern children and adolescents that are eroded by a large amount of sweets, the probability of tooth decay in children gradually increases. It is best to take advantage of the healthy shedding of teeth and store them as soon as possible.
Why cant teeth be extracted when stem cells are needed?
Firstly, there is evidence to suggest that the younger the teeth or donor, the stronger the effectiveness of stem cells. Secondly, the storage of dental stem cells uses teeth that may have been removed by dentists, so there is no need for additional processes or other discomfort or inconvenience.
